A Case of Cutaneous Tuberculosis in a Buruli Ulcer–Endemic Area

نویسندگان

  • Martin W. Bratschi
  • Earnest Njih Tabah
  • Miriam Bolz
  • David Stucki
  • Sonia Borrell
  • Sebastien Gagneux
  • Blanbin Noumen-Djeunga
  • Thomas Junghanss
  • Alphonse Um Boock
  • Gerd Pluschke
چکیده

1 Swiss Tropical and Public Health Institute, Basel, Switzerland, 2 University of Basel, Basel, Switzerland, 3 National Committee for Leprosy, Buruli Ulcer, Yaws and Leishmaniasis Control, Department of Disease Control, Ministry of Public Health, Yaoundé, Cameroon, 4 Bankim District Hospital, Bankim, Cameroon, 5 Universität Heidelberg, Heidelberg, Germany, 6 FAIRMED Africa Regional Office, Yaoundé, Cameroon

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Buruli ulcer is a disabling cutaneous infection caused by Mycobacterium ulcerans, a slow growing environmental mycobacterium. The name originates from the district of Buruli in Uganda, where many of the early cases

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Serological Evaluation of Mycobacterium ulcerans Antigens Identified by Comparative Genomics

A specific and sensitive serodiagnostic test for Mycobacterium ulcerans infection would greatly assist the diagnosis of Buruli ulcer and would also facilitate seroepidemiological surveys. By comparative genomics, we identified 45 potential M. ulcerans specific proteins, of which we were able to express and purify 33 in E. coli. Sera from 30 confirmed Buruli ulcer patients, 24 healthy controls f...

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A rare large cutaneous ulcer from the rural area, Democratic Republic of Congo. What is the diagnosis: Buruli ulcer?

Mycobacterium ulcerans disease, commonly called Buruli ulcer (BU), is a neglected and emergent tropical disease. Buruli ulcer is endemic in the rural wetlands of the tropical countries/regions of Africa, The Americas, Asia, and Australia but is uncommon in non-African countries. Infection with M. ulcerans often leads to extensive destruction of skin and soft tissue with the formation of large u...

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To identify potential reservoirs/vectors of Mycobacterium ulcerans in northern Queensland, Australia, we analyzed environmental samples collected from the Daintree River catchment area, to which Buruli ulcer is endemic, and adjacent coastal lowlands by species-specific PCR. We detected M. ulcerans DNA in soil, mosquitoes, and excreta of bandicoots, which are small terrestrial marsupials.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2012